New therapy may effectively control HIV in Uganda
A multi-national, multi-institutional study led by Weill Cornell Medicine investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in Uganda. The study, published Jan. 30 in the Journal of Antimicrobial Chemotherapy, adds…
Advances in AI can help prepare the world for the next pandemic, global group of scientists find
A study published in Nature today outlines for the first time how advances in AI can accelerate breakthroughs in infectious disease research and outbreak response. The study — which is published following last week’s AI Action Summit and amidst increasing…
‘Healthy’ vitamin B12 levels not enough to ward off neuro decline
Meeting the minimum requirement for vitamin B12, needed to make DNA, red blood cells and nerve tissue, may not actually be enough — particularly if you are older. It may even put you at risk for cognitive impairment. A new…
Newfound circuit better explains how the brain recognizes what is familiar and important
A newly identified part of a brain circuit mixes sensory information, memories, and emotions to tell whether things are familiar or new, and important or just “background noise.” Led by researchers from NYU Langone Health, the work found that a…
Global action needed to solve the medical oxygen crisis
Targets for universal access, national roadmaps and more affordable and accessible care are vital to help fill the medical oxygen gap affecting more than half of the world’s population, according to a new global report. The Lancet Global Health Commission…
This research is absolutely nuts — for better health care
A nut used in herbal tea has become a hydrogel perfect for a variety of biomedical uses in new research from the University of Chicago Pritzker School of Engineering (UChicago PME) and UChicago Chemistry Department. A paper published today in…
Gene therapy for rare epilepsy shows promise in mice
Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death. Most cases are caused by a genetic mutation; Dravet syndrome in particular…
How is vibroacoustic analysis used in engineering?
vibroacoustic analysis used in engineering Vibroacoustic analysis is a critical component of modern engineering, focusing on the interaction between sound waves and structural vibrations. This specialized field is essential for designing and optimizing various mechanical and structural systems to ensure…
Mapping connections in a neuronal network
Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons. The research, published in Nature Biomedical…
Fungus ‘hacks’ natural immune system causing neurodegeneration in fruit flies
A fungal infection has been shown to trigger a fruit fly’s own immune system to destroy brain cells leading to signs of neurodegeneration, a new study has found. The paper published in PLOS Biology today found that a fungus called…
Jacket uses AI to keep you comfortable
Electronic textiles, such as heating pads and electric blankets, can keep the wearer warm and help ease aches and pains. However, prolonged use of these devices could possibly cause heat-related illnesses, including hyperthermia or burns. Recently, a group of researchers…
Brake pad emissions can be more toxic than diesel exhaust
A study by the University of Southampton (UK) has found microscopic particles emitted from certain types of commonly fitted brake pads can be more toxic than those found in diesel vehicle exhaust. The research shows that a higher concentration of…
Mouse study finds impaired cell development: Intermittent fasting could be unsafe for teenagers
A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta…
Biohybrid hand gestures with human muscles
A biohybrid hand which can move objects and do a scissor gesture has been built by a team at the University of Tokyo and Waseda University in Japan. The researchers used thin strings of lab-grown muscle tissue bundled into sushilike…
Dessert stomach emerges in the brain
To find the cause of the “dessert stomach,” the researchers investigated the reaction of mice to sugar and found that completely satiated mice still ate desserts. Investigations of the brain showed that a group of nerve cells, the so-called POMC…
Stronger, safer, smarter: Pioneering Zinc-based dissolvable implants for bone repair
Monash research could transform how broken bones are treated, with the development of a special zinc-based dissolvable material that could replace the metal plates and screws typically used to hold fractured bones together. Surgeons routinely use stainless steel or titanium,…
As more Americans work later in life, poll shows positive health impacts, especially for those over 65
Having a job — whether it’s working for someone else or being their own boss — gives older Americans more than just a way to earn money or get health insurance, a new poll finds. More than two-thirds of those…
Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumour growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA (lncRNA) ‘XIST’ could be an effective therapeutic strategy for treating…
Born to heal: Why babies recover, but adults scar, after heart damage
Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults aren’t so lucky. After a heart attack, most adults struggle to regenerate healthy heart tissue, leading to scar-tissue buildup and, often, heart…
Biomarker test can detect Alzheimer’s pathology earlier
Years before tau tangles show up in brain scans of patients with Alzheimer’s disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms…
Drug may counteract muscle loss and osteoporosis after rapid weight loss
Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study from Aarhus University indicates that the drug…
From muscle to memory: New research uses clues from the body to understand signaling in the brain
Our biceps and our brain cells may have more in common than previously thought. New research led by the Lippincott-Schwartz Lab shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract…
Co-located cell types help drive aggressive brain tumors
A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Mitochondria may hold the key to curing diabetes
Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin…
Potential new pathway to fight viruses
Five years removed from the COVID-19 outbreak, scientists around the world are still studying its effects and, more importantly, ways those effects can be mitigated in the future. An international team of researchers may have just found a critical clue…
Clot-busting meds may be effective up to 24 hours after initial stroke symptoms
The clot-dissolving medication, alteplase, improved stroke patients’ recovery by more than 50% when given up to 24 hours after the beginning of an ischemic stroke, according to preliminary late-breaking science presented today at the American Stroke Association’s International Stroke Conference…
Saving energy is ‘in’, even neurons are joining in
Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the University Medical Center Göttingen found that the…
New computational method reveals congestive heart failure
A team of physicists at Tampere University has developed a groundbreaking method for detecting congestive heart failure with greater ease and precision than previously thought possible. This multidisciplinary study, involving both cardiologists and computational physicists, builds on the team’s earlier…
Scientists discover brain mechanism that helps us overcome fear
Researchers at the Sainsbury Wellcome Centre (SWC) at UCL have unveiled the precise brain mechanisms that enable animals to overcome instinctive fears. Published today in Science, the study in mice could have implications for developing therapeutics for fear-related disorders such…
Scientists reveal gut microbes’ hidden role in anxiety: Could probiotics be the next mental health breakthrough?
Could the key to easing anxiety be hidden in our gut? Scientists from Duke-NUS Medical School and the National Neuroscience Institute have discovered a crucial connection between gut microbes and anxiety-related behaviour. Their research, published today in EMBO Molecular Medicine,…
Researchers discover the brain cells that tell you to stop eating
Columbia scientists have found specialized neurons in the brains of mice that order the animals to stop eating. Though many feeding circuits in the brain are known to play a role in monitoring food intake, the neurons in those circuits…
Pickleball program boosts health and wellness for cancer survivors
A new community-based pickleball program called Project Rally is helping cancer survivors improve their physical and social well-being, according to a recent pilot study led by researchers at Moffitt Cancer Center. The program, which is offered in partnership with the…
Self-assembling cerebral blood vessels: A breakthrough in Alzheimer’s treatment
A 3D model accurately mimicking the Blood-Brain Barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of Mechanical Engineering, Life Sciences, IT Convergence Engineering, and the Graduate School…
Slow traffic, fast food: Study links road delays with unhealthy eating
Ever notice how much more tempting it is to pick up fast food for dinner after being stuck in traffic? It’s not just you. New University of Illinois Urbana-Champaign research shows that traffic delays significantly increase visits to fast food…
Study establishes link between early side effects from prostate cancer radiation and long-term side effects
Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study led by investigators from the UCLA…
The big chill: Is cold-water immersion good for our health?
From early ocean dips to ice-cold polar plunges, cold-water immersion is increasingly popular among athletes and wellness warriors. But how much of the hype is backed by science? In the most comprehensive systematic review and meta-analysis of its kind, University…
Researchers identify protective properties of amniotic fluid
Researchers at Oregon Health & Science University have made new discoveries about amniotic fluid, a substance historically not well understood in medical research due to the difficulty in obtaining it during pregnancy, especially across gestation. Amniotic fluid is the vital…
This delicate nanoflower is downright deadly to bacteria
A carnation-like nanostructure could someday be used in bandages to promote wound healing. Researchers report in ACS Applied Bio Materials that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory and biocompatible properties. They say these results show these tannic…
New research unlocks key to long-lasting immune response in cancer and chronic diseases
Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders — T cells — lose their ability to function effectively. Research, led by the Peter Doherty Institute for Infection…
With generative AI, chemists quickly calculate 3D genomic structures
Every cell in your body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different from a skin cell, are partly determined…
Sound is a primary issue in the lives of skateboarders, study shows
Sound plays a significant and often poignant part of skateboarders’ relationship with their sport, a new study shows. Skateboarders develop the skill to tune into the noise of urban surfaces. They both hear and feel noise and this means images…
Regular dental flossing may lower risk of stroke from blood clots, irregular heartbeats
Flossing your teeth at least once a week may be linked to a lower risk of stroke caused by a blood clot blocking brain blood flow and irregular heartbeats, according to a preliminary study to be presented at the American…
Topical mupirocin lowers lupus inflammation
Systemic lupus erythematosus, more commonly known as lupus, has a variety of symptoms and room for improvement when it comes to treatment. Cutaneous lupus erythematosus is a common manifestation of systemic lupus erythematosus. The condition is characterized by rashes on…
The benefits of speaking multiple languages
Encouraging bilingualism at home can have many cognitive benefits, which may be particularly helpful to kids with autism spectrum disorder (ASD), new research from the University of Miami College of Arts and Sciences indicates. A team of researchers led by…
Advanced brain circuit-mapping technique reveals new anxiety drug target
Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target for treating anxiety disorders and related conditions and demonstrates a general…
Individual cells can be connected to plastic electrodes
Researchers have succeeded in creating a close connection between individual cells and organic electronics. The study lays the foundation for future treatment of neurological and other diseases with very high precision.
Simple ways to improve the wellbeing of pediatric critical care staff
The Staff Wellbeing (SWell) project, led by Aston University researchers in collaboration with Birmingham Children’s Hospital and NHS England, has developed two simple, easy-to-deliver sessions to improve the wellbeing of staff in paediatric critical care (PCC) units in UK hospitals….
Transforming longevity research: AI paves the way for personalized treatments in aging science
A collaborative study between researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and the Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Germany, investigated how advanced AI…
Weight-loss surgery lowers risk of developing complications of liver disease in patients with cirrhosis and obesity
A Cleveland Clinic study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future risk of developing serious liver complications compared with patients who received medical therapy alone. The results were published…
Does At Home Care include medical assistance?
At Home Care At home care services are designed to offer individuals the support they need to remain healthy and independent within the comfort of their own homes. Many families wonder if at-home care includes medical assistance, and the answer…
Sepsis, or death by lethal message
Like a poison pen, dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues in the UConn School of Medicine report in the Jan. 23 issue of Cell. Their findings could lead to…
Study unveils key immune cells found to boost cancer treatment success in acute myeloid leukemia
A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics made a pivotal discovery in the field of cancer immunotherapy. In a paper published today in Science Immunology, the team identified a specific population of immune cells…
Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer
Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The…
VR subway experiment highlights role of sound in disrupting balance for people with inner ear disorder
The vestibular system is a network of organs in the inner ears that detects the motions and position of the head. The brain uses this information, along with inputs from the eyes and joints, to maintain the body’s balance. Visual…
Scientists design peptides to enhance drug efficacy
A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy, as demonstrated in leukemia models. The study, published in the journal Chem, was led by researchers…
Exercise improves brain function, possibly reducing dementia risk
A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function. A study,…
New combination immunotherapy for melanoma and breast cancer
A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed…
Artificial intelligence in biomedicine: A key to analyzing millions of individual cells
In recent years, researchers have made considerable progress with single-cell technology. This makes it possible to investigate tissue on the basis of individual cells and simply to determine the various functions of the individual cell types. The analysis can be…
T cells rise up to fight infections in the gut
Your gut is a battleground. The cells that line your small intestine have to balance two seemingly contradictory jobs: absorbing nutrients from food, while keeping a wary eye out for pathogens trying to invade your body. “This is a surface…
New study uncovers key mechanism behind learning and memory
A breakthrough study published today in the Journal of Neurosciencesheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory. Researchers have identified a…
Can DNA-nanoparticle motors get up to speed with motor proteins?
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion. The DNA-nanoparticle…
Brain immune cells may also be from ‘Mars and Venus’
A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another “crew” of responders is busy clearing debris and repairing injured tissue. This crew is called…
Violence on TV: What happens to children who watch?
Results of new study led by Linda Pagani, Professor at the Université de Montreal’s School of Psychoeducation, long-term associated risks of early exposure to violent content in childhood and later teen antisocial behavior, more than a decade later. “Although past…
Ancient viral DNA shapes early embryo development
Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the “dark side” of the genome, researchers at Helmholtz Munich and…
Extreme rain heightens E. coli risks for communities of color in Texas
Nobody wants to share a day on the water with E. coli. The bacteria is a sure sign of fecal contamination, which is washed into waterways from farm fields or sewage systems by rain. The microbes are also dangerous —…
Immune complex shaves stem cells to protect against cancer
A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators. The…
Insights into how populations conform or go against the crowd
Cultural traits — the information, beliefs, behaviors, customs, and practices that shape the character of a population — are influenced by conformity, the tendency to align with others, or anti-conformity, the choice to deliberately diverge. A new way to model…
Multi-target approach counters tumor growth in several cancers
The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target some…
In the Northeast, 50% of adult ticks carry Lyme disease carrying bacteria
Across most of the Northeast, getting bitten by a blacklegged tick — also called a deer tick — is a risk during spring, summer, and fall. A new Dartmouth study, published in Parasites and Vectors, finds that 50% of adult…
Astronomers capture unprecedented view of supermassive black hole in action
Active galactic nuclei are supermassive black holes at the center of certain galaxies. As matter falls into these black holes, enormous amounts of energy are released, making active galactic nuclei, or AGN, one of the most energetic phenomena that can…
Fine-tuned brain-computer interface makes prosthetic limbs feel more real
You can probably complete an amazing number of tasks with your hands without looking at them. But if you put on gloves that muffle your sense of touch, many of those simple tasks become frustrating. Take away proprioception — your…
Fatal neurodegenerative disease in kids also affects the bowel
ssor of pediatrics, of genetics and of neurology at Washington University School of Medicine in St. Louis. “It can be painful and a serious quality of life issue for the child and their families.” The parent perspective led Cooper on…
Is eating more red meat bad for your brain?
People who eat more red meat, especially processed red meat like bacon, sausage and bologna, are more likely to have a higher risk of cognitive decline and dementia when compared to those who eat very little red meat, according to…
How can Home Health Care improve the quality of life for patients?
How can Home Health Care improve the quality of life for patients? Home Health Care plays a vital role in enhancing the quality of life for patients by providing personalized, compassionate, and convenient care within the comfort of their own…
Researchers identify three psychological profiles that could determine the evolution of mental, cognitive and brain health in aging
An international study published in the journal Nature Mental Health has identified three psychological profiles associated with different patterns of cognitive and brain decline in ageing. The study, which analysed more than 1,000 middle-aged and older adults, shows that the…
Putting a lid on excess cholesterol to halt bladder cancer cell growth
Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth? Previous studies showed that a protein called PIN1 helps cancers initiate and progress, but…
Need for standardized measurement methods in gene therapy
In a finding with implications for one of the most promising cutting-edge medical treatments, researchers evaluated several measurement techniques commonly used in gene therapy. The study determined that one of the most popular techniques was “problematic” and requires further development…
New study identifies how blood vessel dysfunction can worsen chronic disease
Researchers at Oregon Health & Science University have uncovered how specialized cells surrounding small blood vessels, known as perivascular cells, contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis. The findings, published today in Science…
A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor College of Medicine, Texas Children’s Cancer Center and the Center for…
Dementia with Lewy bodies has been difficult to diagnose early, but comprehensive cognitive testing could change that
Cognitive profiles for early diagnosis of Dementia with Lewy bodies (DLB) have been outlined in a new study, out today in Alzheimer’s & Dementia. Although DLB is the second most common neurodegenerative dementia following Alzheimer’s Disease, it is usually misdiagnosed,…
Dangerous bacterial biofilms have a natural enemy
If your teeth have ever felt fuzzy after skipping a brushing, you’ve encountered biofilm — a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on…
Lower access to air conditioning may increase need for emergency care for wildfire smoke exposure
As Los Angeles County battles the most destructive wildfires in its history, a new study suggest that US policies should prioritize equity and education regarding the measures people can take to protect themselves from the harmful pollutants in wildfire smoke….
Feeding your good gut bacteria through fiber in diet may boost body against infections
The group of bacteria called Enterobacteriaceae, including Klebsiella pneumoniae, Shigella, E.coli and others, is present at low levels as part of a healthy human gut microbiome. But at high levels — caused for example by increased inflammation in the body,…
Self-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new University of Pittsburgh research published today in Nature Microbiology. The in-built safety mechanisms circumvent the possibility of an accidental self-infection with weakened…
Medicare rules may reduce prescription steering
Weill Cornell Medicine researchers have found that pharmacy benefit managers (PBMs) — organizations that negotiate access to medicines for most patients in the United States — steer patients to use their own pharmacies. However, these pharmacies appear less used in…
Researchers find betrayal doesn’t necessarily make someone less trustworthy if we benefit
Imagine this scenario: Two people cheat on their partners with each other and then leave their partners to be together. Should they trust each other, or “once a cheater, always a cheater”? Intuition and past research suggest that whether people…
Using robots in nursing homes linked to higher employee retention, better patient care
Facing high employee turnover and an aging population, nursing homes have increasingly turned to robots to complete a variety of care tasks, but few researchers have explored how these technologies impact workers and the quality of care. A new study…
A new era in genetic engineering
Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices. The same is now possible in gene editing. Rather than employ separate tools for editing genes…
How our cells dispose of waste and ways to control it
Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks. This vital process prevents the formation of…
Ketamine use on the rise in U.S. adults; new trends emerge
A recent study analyzing data from the National Survey on Drug Use and Health (NSDUH) found that past-year recreational ketamine use among adults has increased dramatically since 2015, including significant shifts in associations with depression and sociodemographic characteristics such as…
Ultrasound enhances early pregnancy care, cuts emergency visits by 81%
Published in Annals of Family Medicine, a University of Minnesota Medical School research team found that implementing point-of-care ultrasounds (POCUS) to assess the viability and gestational age of pregnancies in the first trimester enhanced care for pregnant patients and cut…
Study finds chemotherapy antidote could improve recovery after chemotherapy-induced kidney toxicity
An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators at Mass General Brigham. Using data from 28 major U.S. cancer centers*,…
New mechanism discovered that triggers immune response in cells with damaged DNA
A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery deepens the understanding of a new type of cell signaling…
Age matters: Kidney disorder indicator gains precision
Annual health checkups regularly include urine tests that serve several purposes, including checking for symptoms of kidney disease. The presence of albumin in the urine is one indicator as is glomerular filtration rate. In diabetic nephropathy, albuminuria first appears, leading…
Approaches against metastatic breast cancer: mini-tumors from circulating cancer cells
Tumor cells circulating in the blood are the “germ cells” of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team from the…
Surprising ‘two-faced’ cancer gene role supports paradigm shift in predicting disease
A genetic fault long believed to drive the development of oesophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer. This unexpected discovery could help doctors identify which individuals…
One of the world’s largest social programs greatly reduced tuberculosis among the most vulnerable
Brazil’s Bolsa Família Program (BFP) is one of the largest conditional cash transfer programmes implemented worldwide. Since 2004, the BFP has provided financial support to the poorest families in Brazil, on the condition that they fulfil certain conditions such as…
Scientists unveil surprising human vs mouse differences in a major cancer immunotherapy target
Since its discovery in the 1990s, “programmed cell death protein 1,” or PD-1, has been regarded as a leading target in cancer treatments. A “checkpoint” receptor that often resides on the surface of immune system cells, the PD-1 molecule works…
AI can improve ovarian cancer diagnoses
A new international study led by researchers at Karolinska Institutet in Sweden shows that AI-based models can outperform human experts at identifying ovarian cancer in ultrasound images. The study is published in Nature Medicine. “Ovarian tumours are common and are…
Research on clozapine safety: Big-data evidence on rare blood cancer cases
An inter-departmental research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has conducted the world’s first analytic real-world cohort study on the association of clozapine, a highly efficacious antipsychotic drug, with the incidence of…
Ancient DNA unlocks new understanding of migrations in the first millennium AD
Researchers can bring together a picture of how people moved across the world by looking at changes in their DNA, but this becomes a lot harder when historical groups of people are genetically very similar. In research published today in…
Key players in brain aging: New research identifies age-related damage on a cellular level
Scientists at the Allen Institute have identified specific cell types in the brain of mice that undergo major changes as they age, along with a specific hot spot where many of those changes occur. The discoveries, published in the journal…
System to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans — including those causing flu, COVID, whooping cough and tuberculosis. The new approach uses samples from infected humans…
People who are immunocompromised may not produce enough protective antibodies against RSV after vaccination
Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity — primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders — do not respond…
Brain structure differences are associated with early use of substances among adolescents
A study of nearly 10,000 adolescents funded by the National Institutes of Health (NIH) has identified distinct differences in the brain structures of those who used substances before age 15 compared to those who did not. Many of these structural…
Preclinical study finds surges in estrogen promote binge drinking in females
The hormone estrogen regulates binge drinking in females, causing them to “pregame” — consume large quantities of alcohol in the first 30 minutes after it’s offered, according to a preclinical study led by scientists at Weill Cornell Medicine. The study…
Adoption of ‘hospital-at-home’ programs remains concentrated among larger, urban, not-for-profit and academic hospitals
Hospitals that have adopted the Center for Medicare and Medicaid (CMS) “hospital-at-home” program, which serves as an alternative to admission to brick-and-mortar facilities, are concentrated in large, urban, not-for-profit, and academic hospitals, new research suggests. The findings are among the…
New research identifies key cellular mechanism driving Alzheimer’s disease
Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer’s disease (AD). The study, published in the journal Neuron,…
Researchers develop tool to fast-track measurement of protein interactions for drug discovery
A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy. Interactions between proteins play a significant role in biological processes,…
High-quality nanodiamonds for bioimaging and quantum sensing applications
Quantum sensing is a rapidly developing field that utilizes the quantum states of particles, such as superposition, entanglement, and spin states, to detect changes in physical, chemical, or biological systems. A promising type of quantum nanosensor is nanodiamonds (NDs) equipped…
New drug to prevent migraine may start working right away
A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at the…
Digital healthcare consultations not enough for safe assessment of tonsillitis
Digital healthcare consultations are not enough for a safe assessment of tonsillitis, according to a study from the University of Gothenburg. Reliability will not be sufficient, thus increasing the risk of over- or undertreatment of a sore throat. Tonsillitis is…
Virus that threatened humanity opens the future
Professor Sangmin Lee from POSTECH’s Department of Chemical Engineering, in collaboration with 2024 Nobel Chemistry Laureate Professor David Baker from the University of Washington, has developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence…
Singles differ in personality traits and life satisfaction compared to partnered people
Although being married or in a long-term relationship is often seen as the norm, more people are staying single for life. But singlehood can bring economic and medical disadvantages, especially as people get older and may become more reliant on…
Scientists discover a ‘Goldilocks’ zone for DNA organization, opening new doors for drug development
In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life:…
New scan method unveils lung function secrets
A new method of scanning lungs is able to show the effects of treatment on lung function in real time and enable experts to see the functioning of transplanted lungs. This could enable medics to identify sooner any decline in…
Foundational technology to make cancer cells revert to normal cells?
Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from…
Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued
A year after becoming available, vaccines to protect against RSV in newborns and older adults are being more widely accepted by the American public, according to a new Annenberg Public Policy Center (APPC) health survey conducted in November 2024. Over…
Propranolol reduces tremors in Parkinson’s disease
The standard medication levodopa does not always work against tremors in Parkinson’s disease, especially in stressful situations. Propranolol, however, does work during stress, providing insight into the role of the stress system in tremors. MRI scans reveal that propranolol directly…
Gene editing tool reduces Alzheimer’s plaque precursor in mice
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer’s disease, researchers at the University of Illinois…
AI may help researchers with medical chart review, study finds
Stanford Medicine researchers have built an artificial intelligence tool that can read thousands of doctors’ notes in electronic medical records and detect trends, providing information that physicians and researchers hope will improve care. Typically, experts seeking answers to questions about…
A tropical disease in Switzerland: Call for coordinated action on Chagas disease
The Swiss Tropical and Public Health Institute (Swiss TPH), in collaboration with the World Health Organization and other partners conducted a comprehensive review of Chagas disease in Switzerland. Although typically found in Latin America, Chagas disease affects between 2,000 and…
Researchers discover replication hubs for human norovirus
Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no approved vaccines or antivirals. Paving the way for improved drug…
Research points the way to lifesaving antiparasitic drugs while unlocking a scientific mystery
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world…
Microscopic discovery in cancer cells could have a big impact
In 2022 alone, over 20 million people were diagnosed with cancer, and nearly 10 million died from the disease, according to the World Health Organization. While the reaches of cancer are massive, the answer to more effective treatments may be…
Can the heart heal itself? New study says it can
A research team co-led by a physician-scientist at the University of Arizona College of Medicine — Tucson’s Sarver Heart Center found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways…
By looking at individual atoms in tooth enamel, researchers are learning what happens to our teeth as we age
Teeth are essential for helping people break down the food they eat, and are protected by enamel, which helps them withstand the large amount of stress they experience as people chew away. Unlike other materials in the body, enamel has…
Brain inflammation alters behavior according to sex, mouse study finds
Inflammation in the hippocampus — the brain’s memory centre — significantly alters motivation and behaviour in mice, including food-seeking behaviour, with notable differences between males and females, a recent study reveals. The hippocampus plays a crucial role in memory formation,…
After lockdown, immune system reacts more strongly to viruses and bacteria
Research from Radboud university medical center shows that the lockdowns during the COVID-19 pandemic had a significant impact on people’s immune response to microorganisms. During the lockdown, inflammation level in the body was low, but afterwards, the immune system reacted…
Human-like artificial intelligence may face greater blame for moral violations
In a new study, participants tended to assign greater blame to artificial intelligences (AIs) involved in real-world moral transgressions when they perceived the AIs as having more human-like minds. Minjoo Joo of Sookmyung Women’s University in Seoul, Korea, presents these…
Developing artificial intelligence tools for health care
Reinforcement Learning, an artificial intelligence approach, has the potential to guide physicians in designing sequential treatment strategies for better patient outcomes but requires significant improvements before it can be applied in clinical settings, finds a new study by Weill Cornell…
Brain cells remain healthy after a month on the International Space Station, but mature faster than brain cells on Earth
Microgravity is known to alter the muscles, bones, the immune system and cognition, but little is known about its specific impact on the brain. To discover how brain cells respond to microgravity, Scripps Research scientists, in collaboration with the New…
Microchips capable of detecting and diagnosing diseases
In a world grappling with a multitude of health threats — ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria — the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where…
The psychological implications of Big Brother’s gaze
A new psychological study has shown that when people know they are under surveillance it generates an automatic response of heightened awareness of being watched, with implications for public mental health. In a paper published in the journal Neuroscience of…
A new twist: The molecular machines that loop our chromosomes also twist DNA
Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make…
Unlocking the potential to better target cancer with immunotherapy
Australian-led research is unlocking new ways for immunotherapy to better target cancer. Cancer immunotherapy has revolutionised treatment for patients, whereby the body’s own immune system is harnessed to destroy cancer cells. Typically, several molecules restrain the ability of T cells…
AI tool analyzes placentas at birth for faster detection of neonatal, maternal problems
A newly developed tool that harnesses computer vision and artificial intelligence (AI) may help clinicians rapidly evaluate placentas at birth, potentially improving neonatal and maternal care, according to new research from scientists at Northwestern Medicine and Penn State. The study,…
Key regulator that induces cancer-killing capacity in T cells under hypoxia is identified
Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective. Thus, finding ways to disarm that resistance and rejuvenate anti-cancer TILs —…
A low omega-6, omega-3 rich diet and fish oil may slow prostate cancer growth
A new study led by UCLA Health Jonsson Comprehensive Cancer Center investigators offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without…
Generic platinum chemotherapy shortages did not increase deaths
During a shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023, there was no difference in mortality rates among patients with advanced cancer compared to the previous year, and prescription rates for the two…
As wildfires intensify, prolonged exposure to pollution linked to premature death
Researchers have found evidence that living in areas prone to wildfire smoke may negatively impact an individual’s life expectancy. In many parts of the contiguous United States, wildfires are rapidly growing more intense, endangering the humans and wildlife that live…
A dial for tuning the immune system: Discovery sheds light on why COVID makes some sicker than others
For years, scientists have looked to a critical piece of immune system machinery — known as the interferon pathway — for answers. There, when our cells sense an infection, they release a protein known as interferon, which warns other cells…
Study finds new blood test predicts prognosis for advanced prostate cancer patients
Published in Nature Communications, a new study led by the University of Minnesota Medical School and Duke University found that a DNA sequencing test for advanced prostate cancer patients can distinguish between patients with poor and favorable prognoses. The new…
Early-onset colorectal cancer cases surge globally
A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease. In 14…
Enabling AI to explain its predictions in plain language
Machine-learning models can make mistakes and be difficult to use, so scientists have developed explanation methods to help users understand when and how they should trust a model’s predictions. These explanations are often complex, however, perhaps containing information about hundreds…
Social factors affect pediatric cardiac arrest outcomes
The odds on whether a child survives a cardiac arrest may depend on where they live, according to a new study from the University of Missouri School of Medicine. This study found that certain social factors that influence health are…
Researchers ‘see’ vulnerability to gaming addiction in the adolescent brain
Playing video games is a rite of passage for many adolescents, but for some, it could also be the first step to a gaming addiction. “A number one concern for parents of children and teenagers is how much screen time…
Study helps solve mystery between repeated head impacts in sports and location of brain degeneration in CTE
A new study from researchers at the Boston University Alzheimer’s Disease and CTE Center is helping solve the mystery as to why the brain shrinks in a unique pattern, known as atrophy, in chronic traumatic encephalopathy (CTE). Published in Acta…
A healthy diet helps the weighty battle with chronic pain
Chronic pain is an acute and debilitating condition that affects millions of people worldwide. And while pain interventions are available, many people struggle without treatment at all. Now new research from the University of South Australia shows that adopting a…
CAST mouse model: A crucial tool for future COVID-19 outbreaks
Researchers at The Jackson Laboratory and Trudeau Institute have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development, reported in Scientific Reports, marks a pivotal step forward in infectious disease…
Getting to the bottom of things: Latrine findings help researcher trace the movement of people and disease
A McMaster researcher has uncovered evidence of intestinal parasites in a 500-year-old latrine from Bruges, Belgium, and while the finding may induce queasiness in some, it is expected to provide important scientific evidence on how infectious diseases once spread through…
Why people remember certain things and not others
Exactly why do people remember what they remember? A recently published review paper from researchers at Rice University sheds light on this fundamental question and the relationship between factors that influence human memory. “Tell me why: The missing w in…
Early detection of high-altitude hypoxic brain injury
People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury. By using in vivo electrochemistry, researchers demonstrated that characteristic changes occur in the oxygen content of various brain regions before…
MRI could be key to understanding the impact a gluten free diet has on people with Celiac disease
Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with coeliac disease, which could be the first step towards finding new ways of treating the condition. The MARCO study —…
Molecular zip code draws killer T cells straight to brain tumors
Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice. The technology will soon be tested in a clinical trial for people with glioblastoma. UCSF scientists have developed a…
Mothers massively change their intestines during pregnancy and nursing
When women are pregnant and nurse their babies, their bodies change and various organs, such as the breasts or the immune system, are adapted to ensure the health of both mother and child. This happens throughout evolution in all mammals….
Natural ‘biopesticide’ against malaria mosquitoes successful in early field tests
An experimental bacteria-derived biopesticide is highly effective in killing malaria-carrying mosquitoes, including those that have developed resistance to chemical pesticides, according to initial field tests led by researchers at the Johns Hopkins Bloomberg School of Public Health. The biopesticide is…
Eating high-processed foods impacts muscle quality, study finds
A diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of the amount of calories consumed or level of physical activity, according to a study being presented today at the annual meeting…
Tiny, daily bursts of vigorous incidental physical activity could almost halve cardiovascular risk in middle-aged women
An average of four minutes of incidental vigorous physical activity a day could almost halve the risk of major cardiovascular events, such as heart attacks, for middle-aged women who do not engage in structured exercise, according to new research from…
Research on neurodegeneration in spider brain leads neuroscientists to groundbreaking new discovery in Alzheimer’s-affected human brains
Researchers from Saint Michael’s College and the University of Vermont have made a groundbreaking new discovery that provides a better understanding of how Alzheimer’s disease develops in the human brain. Guided by previous research of spider brains, the scientists uncovered…
How a middle schooler found a new compound in a piece of goose poop
A group of young students became bonafide biomedical scientists before they even started high school. Through a partnership with a nearby university, the middle schoolers collected and analyzed environmental samples to find new antibiotic candidates. One unique sample, goose poop…
Even low levels of arsenic in drinking water raise kidney cancer risk
New research findings from the Texas A&M University School of Public Health indicate that exposure to even low levels of arsenic poses significant health risks, including an increased risk of kidney cancer. The incidence of kidney cancer in the United…
First new treatment for asthma attacks in 50 years
An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%. The findings, published today in The Lancet Respiratory Medicine, could be “game-changing” for…
Clinical trial reveals twice-yearly injection to be 96% effective in HIV prevention
For oral medications that prevent new HIV infection to be effective, the patient must take certain actions, including attending doctor’s visits every three months and — most importantly — consistency. These daily oral antiretrovirals, more commonly referred to as PrEP…
Preschool education: A key to supporting allophone children
Learning French while also developing language skills in one’s mother tongue is no easy task. As a result, allophone children often face learning and communication difficulties in kindergarten, which can negatively impact their educational journey. However, solutions are emerging. According…
Hormone therapy affects the metabolic health of transgender individuals, study finds
New research from Karolinska Institutet shows that long-term sex hormone treatment in transgender individuals can lead to significant changes in body composition and risk factors for cardiovascular disease, particularly in transgender men. The study is published in the Journal of…
Structural link for initiation of protein synthesis in bacteria
Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has…
Bacteria ditch tags to dodge antibiotics
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of antibiotic…
Gold beats platinum for chemo drugs in new lab study
A new gold-based drug can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a study by Australian and Indian researchers. The RMIT University study published in the European Journal of…
Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry
A tiny, four-fingered “hand” folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, University of Illinois Urbana-Champaign…
For those with CTE, family history of mental illness tied to aggression in middle age
People who have chronic traumatic encephalopathy (CTE) who have a family history of mental illness may have a higher risk of aggression in middle age, according to a study published in the November 27, 2024, online issue of Neurology®, the…
Sound of traffic increases stress and anxiety, study finds
Manmade sounds such vehicle traffic can mask the positive impact of nature soundscapes on people’s stress and anxiety, according to a new study published November 27, 2024, in the open-access journal PLOS ONE by Paul Lintott of the University of…
Long COVID brain fog linked to lung function
In patients with long COVID, lower pulmonary gas exchange may be associated with impaired cognitive function, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA). According to the National…
How long ring fingers can point to a love of alcohol
The length of your fingers may hold a vital clue to your drinking habits, according to a new study. There is evidence that alcohol consumption is influenced by prenatal sex steroids so experts from Swansea University and colleagues from the…
Potential new biomarker for psychosis diagnosis
The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are pointing toward a…
Revolutionary bioengineering research may transform type 1 diabetes care, pave way for tackling cancer and autoimmune disease
Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options…
New model of neuronal circuit provides insight on eye movement
Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes’ gaze. The study, published Nov. 22 in Nature Neuroscience, found that a…
Scientists identify key mechanism in development of skin cancer
LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer. Melanoma arising from pigment-producing cells known as melanocytes is the deadliest form of skin cancer. A major cause…
New insights into sleep uncover key mechanisms related to cognitive function
While it’s well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored. A new study by a team of researchers at Rice University and Houston Methodist’s Center…
How Golgi stress affects T-cells’ tumor-fighting ability
The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that’s within or outside of the cell. It’s a core function, but little studied in the setting of cancer immunology, especially when compared to…
Troubling spike in severe pregnancy-related complications
A new study from Northwestern Medicine reveals a troubling rise in severe maternal health issues and birth complications in Illinois from 2016 to 2023, closely linked to increases in chronic health conditions affecting pregnancy, such as high blood pressure, gestational…
Overthinking what you said? It’s your ‘lizard brain’ talking to newer, advanced parts of your brain
We’ve all been there. Moments after leaving a party, your brain is suddenly filled with intrusive thoughts about what others were thinking. “Did they think I talked too much?” “Did my joke offend them?” “Were they having a good time?”…
From food crops to cancer clinics: Lessons in extermination resistance
Just as crop-devouring insects evolve to resist pesticides, cancer cells can increase their lethality by developing resistance to treatment. In fact, most deaths from cancer are caused by the evolution of therapeutic resistance. In a new review, Arizona State University…
Study uncovers potential new target for treatment of chronic, debilitating skin disease
A team of researchers at Clemson University used an innovative multiomics approach to identify key immune mechanisms in a chronic and debilitating inflammatory skin condition. The research, which was published in the journal Proceedings of the National Academy of Sciences…
Weight-loss drug reduces risk of early death for patients with heart failure, trial finds
Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with heart failure, preserved heart pump function and obesity, new research from UVA Health reveals. The drug, from pharmaceutical company Eli Lilly and…
Preterm birth associated with increased mortality risk into adulthood
According to a new study from researchers at Wake Forest University School of Medicine and The Hospital for Sick Children (SickKids) in Toronto, being born preterm is associated with an increased risk of death from birth until the third and…
Changing the definition of cerebral palsy
In the United States, there are currently more adults living with cerebral palsy than children. Despite this, the Centers for Disease Control and Prevention still label cerebral palsy as “the most common motor disability in childhood.” This definition not only…
Study identifies potential new drug for Parkinson’s-related cognitive decline, dementia
A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson’s…
Cocoa or green tea could protect you from the negative effects of fatty foods during mental stress
New research has found that a flavanol-rich cocoa drink can protect the body’s vasculature against stress even after eating high-fat food. Food choices made during periods of stress can influence the effect of stress on cardiovascular health. For example, recent…
Diagnosing knee abnormalities like an experienced radiologist: A novel deep learning model
Multi-sequence knee magnetic resonance imaging (MRI) is an advanced non-invasive diagnostic method for knee pathology. However, MRI interpretation is highly time-consuming and heavily dependent on expertise. A research team from the School of Engineering, the Hong Kong University of Science…
Traditional Mayan practices have long promoted unique levels of family harmony: But what effect is globalization having?
A new paper in the journal Child Development shows how some aspects of family interaction among Indigenous people in Guatemala have fundamentally shifted with rapid globalization, yet families have still maintained a unique level of harmony in their interactions. UC…
Achilles heel of antibiotic-resistant bacteria
Recent estimates indicate that deadly antibiotic-resistant infections will rapidly escalate over the next quarter century. More than 1 million people died from drug-resistant infections each year from 1990 to 2021, a recent study reported, with new projections surging to nearly…
Climate change and eye maladies
Clinical visits by patients suffering ocular surface eye conditions more than doubled during times when ambient particulate matter from air pollution was in the atmosphere, signaling a possible association between climate change and ocular health, according to a new study…
‘Jekyll and Hyde’ leaders do lasting damage, new research shows
There’s only one thing worse than an abusive boss — and that’s a boss who thinks they can make up for their bad behavior by turning on the charm the following day. That’s the key finding from a new study…
New study shows how salmonella tricks gut defenses to cause infection
A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present. The research, published in the Proceedings of the National Academy of Sciences, explains…
Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness
A novel test developed by Duke-NUS researchers enables real-time monitoring of T cells that have been engineered to fight cancer, after re-introduction into the body of a cancer patient. This simple and innovative test provides clinicians with the ability to…
New discovery enables gene therapy for muscular dystrophies, other disorders
Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is a big problem: size. The genes that are dysfunctional in muscular dystrophies are often extremely large, and current delivery methods can’t courier such…
It’s my brain’s fault! Why teenagers make often unwise decisions
Adults exhibit a general tendency to make better decisions than adolescents, and this improvement drives an increase in specific and more sophisticated choice behaviors, according to a study published November 14 in the open-access journal PLOS Biology by Vanessa Scholz…
Children’s gut bacteria may hold the key to diarrhea treatment
Diarrhea claims the lives of 500,000 children each year in low- and middle-income countries. Now, Danish and Ethiopian researchers have linked chronic diarrhea to a specific pattern of gut bacteria, a discovery that could pave the way for new treatments…
Organ donation: Opt-out defaults do not increase donation rates, study finds
A recent study by the Max Planck Institute for Human Development, in collaboration with the MSB Medical School Berlin and the Max Planck UCL Centre for Computational Psychiatry and Ageing Research, shows that switching to an opt-out organ donation policy,…